Assessment of Intracardiac Hemodynamics and Electrolyte Balance in Various Hemodynamic Types of Chronic Heart Failure Accompanied By Anemia
Keywords:
chronic heart failure, chronic kidney disease, kidney dysfunction, fibrosis markers, cystatin-S, TGF-β1, ferrokinetic markers, galectin-3, types of hemodynamicsAbstract
Markers of renal fibrosis were evaluated in dynamics in order to study specific changes in the kidneys of patients with various hemodynamic types and functional classes of chronic heart failure with anemia and to evaluate the effectiveness of treatment with the drug exex. It was found that the marker of renal fibrosis TGF-β1 is 2591.0±108.4 and 755.0±18.87 PG/ml, respectively (p0,01), when the indicators of chronic heart failure in the blood were without anemia and anemia. This was evidenced by the process of fibrosis that occurred in the kidneys. After complex treatment with the addition of iron preparation, the TGF-β1 index decreased by 2.25 times (p0, 01), the clinical condition, quality of life and indicators of resistance to physical exertion significantly changed in a positive direction.
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